A variety of tools are available online to study the varying aspects such as:
- Protein identification and characterizationFindMod: Predict potential protein post-translational modifications and potential single amino acid substitutions in peptides.
- DNA ProteinTranslate: Translates a nucleotide sequence to a protein sequence
- Post-translational modification predictionChloroP: Prediction of chloroplast transit peptidesLipoP: Prediction of lipoproteins and signal peptides in Gram-negative bacteriaMITOPROT: Prediction of mitochondrial targeting sequences
- Topology predictionNetNES: Leucine-rich nuclear export signals (NES) in eukaryotic proteinsPSORT: Prediction of protein sub-cellular localization
- Primary structure analysisProtParam: Physico-chemical parameters of a protein sequence (amino acid and atomic compositions, isoelectric point, extinction coefficient, etc.)
- Secondary structure predictionAGADIR: An algorithm to predict the helical content of peptidesAPSSP: Advanced Protein Secondary Structure Prediction Server
- Tertiary structure prediction-Homology modellingSWISS-MODEL: An automated knowledge-based protein modelling server.
- Molecular modelling and visualization toolsSwiss-PdbViewer: A programme to display, analyse and superimpose protein 3D structuresSwissDock: Docking of small ligands into protein active sites with EADock DSSSwissParam: Topology and parameters for small molecules
- Prediction of disordered regionsDisEMBL: Protein disorder prediction
- Alignment analysisAMAS: Analyse Multiply Aligned Sequences
- Phylogenetic analysisBIONJ: Server for NJ phylogenetic analysis
- Biological text analysisAcroMed: A computer-generated database of biomedical acronyms and the associated long forms extracted from the recent Medline abstracts
- Statistical toolspROC: A package to visualize, smooth and compare receiver operating characteristic (ROC curves)
PROTEOMICS TOOLS